Atopic dermatitis (AD) is a complex inflammatory skin condition that is not fully understood. Epidermal barrier defects and Th2 immune response dysregulations are thought to play crucial roles in the pathogenesis of the disease. A vicious circle takes place between these alterations. and it can further be complicated by additional genetic and environmental factors. https://www.spidertattooz.com/Patchwork-Barn-Quilt-Pattern-by-Edyta-Sitar/